20 Times More Muscle Strength
A synergistic and patent protected combination of two natural ingredient
Turns On mTOR Signaling To Stimulate Muscle Protein Synthesis In Skeletal Muscle Cells
Activates Endothelial Nitric Oxide Synthase (Enos) To Improve Blood Flow & Reduce Fatigue
Improves Serum Testosterone
Activates AMPK in Skeletal Muscle Cells
May Reduce Muscle Wasting Via Inhibition Of Ubiquitin
Cindura offers un parallel advantage as it can be formulated in Capsules, Tablets, Powder, Shots and many exciting forms of food and beverages.
A double blinded placebo controlled clinical study in healthy trained subjects demonstrated efficacy and tolerability of CinDura®
Day-0 Screening; Day-7 Baseline; Day-21 (follow up after 2 weeks);
Day-35 (follow up after 4 weeks) and Day-49 (follow up after 6 weeks)
Bar diagram represents mean change in muscle strength by 1-RM bench press in Placebo and CinDura® groups from baseline to Day 49. Each bar represents mean ± SD, *p<0.05 (ANCOVA) indicates change in muscular strength in treatment group was significant over placebo
Bar diagram represents mean change in muscle strength by 1-RM leg press in Placebo and CinDura® groups
from baseline to Day 49. Each bar represents mean ± SD, *p<0.05 (ANCOVA) indicates change in muscular
strength in treatment group was significant over placebo
Bar diagram represents mean change in time to exhaust in Placebo and CinDura® groups from baseline to
Day 49. Exhaust time was measured as time of continuous treadmill exercise with increase in inclination every
5 minutes. The change in treadmill exhaust time of treatment group in comparison with the Placebo was
tested using ANCOVA;*p<0.05
Bar diagrams represent free testosterone level in circulation of resistance trained participants. Bars represent
mean±SD of free testosterone concentrations in the placebo and CinDura groups at baseline and at day 49. *
indicates significance (P<0.05 ) over baseline in un-paired t-test.
Bar diagrams represent mean change (cm) in left arm and right arm circumference respectively in Placebo
and CinDura® groups from baseline to Day 49. Each bar represents mean ± SD, *p<0.05 (ANCOVA) indicates
change in arm girth in treatment group was significant over placebo.
Bar diagrams represent mean change (kg) in Lean body mass and fat mass respectively in Placebo and
CinDura® groups from baseline to Day 49. The bars represent mean changes (± SD) from baseline Lean Body
Mass and Total Body Fat at day 49. Comparison between the groups were analyzed using ANCOVA; *P<0.05
CinDura® is safe for human consumption
Healthy Swiss albino mice were randomly divided into three groups
(n=5). Mice were treated with:
The bar diagrams A and B represent Average Swimming Velocity and Total distance travelled respectively.
The bars 1 to 3 represents vehicle control, CinDura® (150 mg/kg ) and Caffeine (10 mg/kg) treated groups
respectively. Each bar represents Mean ± SEM, n=5.
CinDura® activates cellular protein
synthesis machinery through
activation of mTOR signaling, helping
increased protein synthesis in skeletal
muscle cells
CinDura® improves skeletal muscle
development through
up-regulation of transcription factors
involved in myogenesis
Phase contrast micrographs showing Myotube formation in C2C12 mouse myoblasts; Vehicle, 10 and 100 ng/ml Cindura® (A, B & C respectively) Immunofluorescence images showing Myosin Heavy Chain protein expression in Vehicle, 10 and 100 ng/ml Cindura® treated C2C12 cells (D, E & F respectively) Arrow heads indicate multinucleated myotubes
CinDura® induces myotube formation in myoblasts indicating support for
building skeletal muscle fibers
CinDura® might reduce muscle wasting via inhibiting the Ubiquitin
Proteasome Pathway as shown in L6 rat skeletal myoblasts
CinDura® helps recovering from H2O2 induced depolarized mitochondrial
membrane in L6 rat skeletal myoblasts, thus maintaining healthy mitochondrial
function under oxidative stress, e.g. during prolonged workout
CinDura® activates AMPK in skeletal
muscle cells, indicating increase in
glucose uptake, fatty acid oxidation,
and mitochondrial biogenesis
CinDura® increases Testosterone production in MA10 mouse leydig cells
CinDura® might reduce muscle wasting via inhibiting the Ubiquitin
Proteasome Pathway
CinDura® exhibited dose dependent free radical scavenging activity by
increase in concentration
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